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Table 1 Comparison between Bodner and colleagues’ [2] analysis of 116 reported cases of squamous cell carcinoma arising in an odontogenic cyst and the present case

From: Squamous cell carcinoma arising from a keratocystic odontogenic tumor: a case report

Feature

Literature review

 

Present case

Comment

Age

Mean age

60.2 years

50 years

Close to mean age

Commonest age of occurrence

6–8th decades

Gender

Male

68%

Female

Male predilection

Female

36%

Site

Mandible

79%

Mandible

 

Maxilla

21%

Type of cyst

Radicular cyst

60%

KCOT

KCOT malignant transformation rate is rare

Dentigerous cyst

16%

KCOT

14%

Lateral periodontal

1%

Unclassified

9%

Histopathologically

Carcinoma in situ

3%

Moderately differentiated SCC

 

Well-differentiated SCC

45%

Moderately differentiated SCC

40%

Poorly differentiated SCC

7%

Verrucous carcinoma

3%

Spindle cell carcinoma

1%

Signs and symptoms

Asymptomatic

11%

Mass paresthesia present in the lower lip

Mass

32%

Pain

24%

Painful mass

16%

Jaw expansion

14%

Sensory disturbance

3%

Treatment modality

Surgery alone

46%

Surgery with neck dissection

 

Surgery with radiotherapy

38%

Surgery, radiotherapy with chemotherapy

6%

Surgery with chemotherapy

6%

Radiotherapy alone

4%

Neck dissection

51%

Overall survival

2 years

62%

1.5 years

Patient still under review

5 years

28%

  1. KCOT keratocystic odontogenic tumor, SCC squamous cell carcinoma