From: Squamous cell carcinoma arising from a keratocystic odontogenic tumor: a case report
Feature | Literature review | Present case | Comment | |
---|---|---|---|---|
Age | Mean age | 60.2 years | 50 years | Close to mean age |
Commonest age of occurrence | 6–8th decades | |||
Gender | Male | 68% | Female | Male predilection |
Female | 36% | |||
Site | Mandible | 79% | Mandible | |
Maxilla | 21% | |||
Type of cyst | Radicular cyst | 60% | KCOT | KCOT malignant transformation rate is rare |
Dentigerous cyst | 16% | |||
KCOT | 14% | |||
Lateral periodontal | 1% | |||
Unclassified | 9% | |||
Histopathologically | Carcinoma in situ | 3% | Moderately differentiated SCC | |
Well-differentiated SCC | 45% | |||
Moderately differentiated SCC | 40% | |||
Poorly differentiated SCC | 7% | |||
Verrucous carcinoma | 3% | |||
Spindle cell carcinoma | 1% | |||
Signs and symptoms | Asymptomatic | 11% | Mass paresthesia present in the lower lip | |
Mass | 32% | |||
Pain | 24% | |||
Painful mass | 16% | |||
Jaw expansion | 14% | |||
Sensory disturbance | 3% | |||
Treatment modality | Surgery alone | 46% | Surgery with neck dissection | |
Surgery with radiotherapy | 38% | |||
Surgery, radiotherapy with chemotherapy | 6% | |||
Surgery with chemotherapy | 6% | |||
Radiotherapy alone | 4% | |||
Neck dissection | 51% | |||
Overall survival | 2 years | 62% | 1.5 years | Patient still under review |
5 years | 28% |