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Table 1 Literature review of other reported cases of advanced cystic adenoid carcinoma of the breast

From: Adenoid cystic carcinoma of the breast – an aggressive presentation with pulmonary, kidney, and brain metastases: a case report

Cases

Patient (age (years)/gender)

Distant metastasis

Treatment

Survival/prognostic

Time to relapse

Herzberg et al. [9]

57, female

Kidney

Mastectomy/nephrectomy

5-year disease-free survival, then lost to follow-up

Distant relapse: 6 years

Vranic et al. [10]

76, female

Kidney

Mastectomy/radical nephrectomy

No information after relapse

Distant relapse: 5 years

Koller et al. [11]

49, female

Brain, lungs

Breast surgery/Chemotherapy/radiation/left parieto-occipital craniotomy

No relapse at 20 months from the surgery

Local relapse: 1 year. Distant relapse: 8 years

Silva et al. [12]

37, female

Brain, liver, lungs, bone

Radical mastectomy/adjuvant chemotherapy (six cycles of adriamycin and cyclophosphamide)/radiotherapy/palliative chemotherapy (docetaxel plus vinorelbine and 5FU in second line)

The patient died 1 year after developing brain metastasis

Distant relapse: 2 years

Our case

65, female

Brain, lung, kidney

Mastectomy/palliative chemotherapy (mitoxantrone)/thoracotomy/radical nephrectomy/craniotomy plus radiotherapy

Patient still alive, now presenting liver lesions

Local relapse: 4 years. Distant relapses: 5 years

  1. 5FU 5-fluorouracil