Paradoxical worsening of hypoxemia in a patient treated by noninvasive positive pressure ventilation for obesity hypoventilation syndrome with concomitant obstructive sleep apnea: a case report

Table 1 Time-course of arterial blood gas values and expiratory/inspiratory positive airway pressures used for noninvasive positive pressure ventilation

	PaO₂ mmHg	PaCO₂ mmHg	Hemoglobin oxygen saturation %	NPPV	Duration of NPPV use	EPAP cm H₂O	IPAP cm H₂O	AHI
January 2015	78.4	48	95.5	0	/	/	/	37
May 2015	87	43	97	+	5 hours 18 minutes	7	16	5.7
December 2015	53.7	42.8	90	+	3 hours 30 minutes	7	16	5
August 2016	85	45.7	96.7	+	4 hours 39 minutes	6	12	3.4

AHI apnea/hypopnea index, EPAP expiratory positive airway pressure, IPAP inspiratory positive airway pressure, NPPV noninvasive positive pressure ventilation, PaCO ₂ carbon dioxide pressure in the systemic arterial blood, PaO ₂ oxygen pressure in the systemic arterial blood

ISSN: 1752-1947