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Table 1 Clinical course and treatment schedule

From: Conventional osteosarcoma of the mandible successfully treated with radical surgery and adjuvant chemotherapy after responding poorly to neoadjuvant chemotherapy: a case report

 

HD-MTX

HD-MTX

CDDP+ADR

Surgery

IFO

IFO

CDDP+ADR

IFO

IFO

CDDP+ADR

IFO

IFO

Leukopenia

-

-

G1

 

G4

G4

G3

G4

G4

G4

G4

G4

Neutropenia

-

G2

G2

 

G4

G4

G2

G4

G4

G4

G4

G4

Platelet

-

-

-

 

-

-

-

-

-

-

G3

G4

Vomiting

-

-

-

 

G2

G2

-

G1

G1

-

G2

G2

Anemia

-

-

-

 

-

-

-

-

-

-

 

G4

  1. ADR adriamycin, CDDP cisplatin, G1 Grade 1, G2 Grade 2, G3 Grade 3, G4 Grade 4, HD high-dose, IFO ifosfamide, MTX methotrexate. Regimen-related toxicity was graded according to the common terminology criteria for adverse events (CTCAE)