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Table 1 Diagnostic criteria for Sweet’s syndrome [2]

From: Serum cytokine profile in pediatric Sweet’s syndrome: a case report

Major criteria are as follows:

• Abrupt onset of tender or painful erythematous plaques or nodules, occasionally with vesicles, pustules, or bullae

• Predominantly neutrophilic infiltration in the dermis without leukocytoclastic vasculitis

Minor criteria are as follows:

• Preceding nonspecific respiratory or gastrointestinal tract infection, or vaccination, or associated with inflammatory disease, hemoproliferative disorders, solid malignant tumors, or pregnancy

• Periods of general malaise and fever (body temperature >38 °C)

• Meeting three out of the following four laboratory values during onset is necessary; 1) an erythrocyte sedimentation rate >20 mm, 2) positive C-reactive protein (CRP) result, 3) segmented nuclear neutrophils, bands >70% in peripheral blood smears, and 4) leukocytosis (count >8000/μL)

• Excellent response to treatment with systemic corticosteroids or potassium iodide

  1. Both major and two minor criteria are needed for diagnosis