From: Serum cytokine profile in pediatric Sweet’s syndrome: a case report
Major criteria are as follows: |
• Abrupt onset of tender or painful erythematous plaques or nodules, occasionally with vesicles, pustules, or bullae |
• Predominantly neutrophilic infiltration in the dermis without leukocytoclastic vasculitis |
Minor criteria are as follows: |
• Preceding nonspecific respiratory or gastrointestinal tract infection, or vaccination, or associated with inflammatory disease, hemoproliferative disorders, solid malignant tumors, or pregnancy |
• Periods of general malaise and fever (body temperature >38 °C) |
• Meeting three out of the following four laboratory values during onset is necessary; 1) an erythrocyte sedimentation rate >20 mm, 2) positive C-reactive protein (CRP) result, 3) segmented nuclear neutrophils, bands >70% in peripheral blood smears, and 4) leukocytosis (count >8000/μL) |
• Excellent response to treatment with systemic corticosteroids or potassium iodide |