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Table 1 Characteristics of patients with Goodpasture’s syndrome complicated with pre-existing interstitial pneumonia

From: Pre-existing chronic interstitial pneumonia is a poor prognostic factor of Goodpasture’s syndrome: a case report and review of the literature

 

Age

Gender (M/F)

Smoking (pack year)

MPO-ANCA

Type of interstitial pneumonia

Duration from onset of IP to GPS

CGN

DAH

Treatments

Survival duration

Cause of death

Reference

1

78

M

50

+

UIP

8 years

+

+

CS, PE, HD, MV

3 months

Respiratory failure

[10]

2

64

M

60

+

UIP

2 months

+

+

CS, HD

3 months

Respiratory failure

[10]

3

72

M

45

+

UIP

N.A.

+

+

CS, PE, HD

6 years

Leukemia

[10]

4

42

F

Never

+

UIP

N.A.

+

+

CS, HD

Alive

N.A.

[10]

5

55

M

30

+

NSIP

9 years

+

+

CS, CY, PE, HD, MV

1 months

Respiratory failure

[11]

6

78

M

102

+

UIP

4 years

+

+

HD, CS

6 months

Respiratory failure

[12]

7

71

M

50

+

UIP

7 years

+

+

CS, PE, HD, MV

7 days

Respiratory failure

present case

  1. CGN crescentic glomerulonephritis, CS corticosteroid, CY cyclophosphamide, DAH diffuse alveolar hemorrhage, F female, GPS Goodpasture’s syndrome, HD hemodialysis, IP interstitial pneumonia, M male, MPO-ANCA myeloperoxidase anti-neutrophil cytoplasmic antibody, MV mechanical ventilation, N.A. not available, NSIP non-specific interstitial pneumonia, PE plasma exchange, UIP usual interstitial pneumonia