Fig. 4
At recurrence the patient had multiple small metastases in both lungs (red arrows) and multiple subcutaneous nodules in her left groin and thigh (white arrows). There was no effect of chemotherapy and only 2 months’ effect of dabrafenib. Panels a and b show before treatment with ipilimumab and c and d after two cycles where a significant remission was seen. After four cycles she was completely tumor free, and still is with virtually no side effects