Fig. 2
From: Classical Hodgkin lymphoma masquerading as chronic recurrent multifocal osteomyelitis: a case report
As seen in Panel a, low-powered field of the gross bone specimen showing lymphoid tissue nodule (arrow) surrounded by faint bands of collagen. Classic multinucleated and bi-lobed Reed–Sternberg cells with surrounding lacunae (Panel b, solid arrows) are shown in a background of a heterogeneous inflammatory infiltrate. A mummified Reed–Sternberg cell is shown (Panel b, open arrow). Further immunohistochemical staining showed positive cluster of differentiation 15 (Panel c) and membrane-distributed cluster of differentiation 30 (Panel d) Reed–Sternberg cells characteristic of classical Hodgkin lymphoma