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Table 1 Hematological and spleen parameters over time on treatment

From: Combination therapy in a patient with chronic neuronopathic Gaucher disease: a case report

Age, months (time point)

Hb (g/dl)

PLT (Ă—103 ÎĽl)

MCV (fl)

ACE (U/L)

Spleen diameter (cm)

17 (diagnosis)

10.7

185

60.3

–

Enlarged

18 (ERT)

10.5

123

70.6

110

10.4

24 (SRT)

12.2

289

67.5

–

11.0

32

12.3

225

71.1

90

9.5

39

12.7

222

70.6

–

–

45

12.3

246

74.9

90

9.7

51

12.7

256

79.6

–

–

59

12.7

342

74.6

75

8.8

65

12.4

235

75.4

–

–

72

12.8

261

77.4

48

9.5

80

13.5

312

78.7

–

–

  1. Hemoglobin (Hb), platelets (PLT), median corpuscular volume (MCV), angiotensin-converting enzyme (ACE) activity, and echographic measures of spleen diameter were evaluated approximately every 6 months (12 months for ACE and spleen diameter after the first year on therapy). The data showed an improvement in all parameters