Fig. 2
From: Intramammary metastatic melanoma of unknown primary origin in a 58-year old patient: a case report
a Macroscopy of the tumor. The cut section of the breast tumor is nodular, tan to gray and more or less well-demarcated. b Standard histology. The tumor cells are very anisokaryotic with abundant eosinophilic cytoplasm and numerous often atypical mitoses (hematoxylin and eosin (H&E), ×40). c Immunohistochemistry. All tumor cells are strongly immunoreactive for S-100 in the cytoplasm and in the nuclei (S-100, ×40)