TY - JOUR AU - Ohara, Nobumasa AU - Uemura, Yasuyuki AU - Mezaki, Naomi AU - Kimura, Keita AU - Kaneko, Masanori AU - Kuwano, Hirohiko AU - Ebe, Katsuya AU - Fujita, Toshio AU - Komeyama, Takeshi AU - Usuda, Hiroyuki AU - Yamazaki, Yuto AU - Maekawa, Takashi AU - Sasano, Hironobu AU - Kaneko, Kenzo AU - Kamoi, Kyuzi PY - 2016 DA - 2016/10/12 TI - Histopathological analysis of spontaneous large necrosis of adrenal pheochromocytoma manifested as acute attacks of alternating hypertension and hypotension: a case report JO - Journal of Medical Case Reports SP - 279 VL - 10 IS - 1 AB - Pheochromocytomas are rare catecholamine-producing neuroendocrine tumors. Hypertension secondary to pheochromocytoma is often paroxysmal, and patients occasionally present with sudden attacks of alternating hypertension and hypotension. Spontaneous, extensive necrosis within the tumor that is associated with catecholamine crisis is an infrequent complication of adrenal pheochromocytoma, but its pathogenesis remains unclear. SN - 1752-1947 UR - https://doi.org/10.1186/s13256-016-1068-3 DO - 10.1186/s13256-016-1068-3 ID - Ohara2016 ER -