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Table 3 Timeline

From: The effects of liraglutide on both hypereosinophilic insulin allergy and the characteristics of anti-insulin antibodies in type 2 diabetes mellitus: a case report

Time

Diabetes-related medical history

1980s

Onset of type 2 diabetes mellitus

2009

Coronary artery bypass grafting was conducted, anaphylaxis induced by intravenous protamine sulfate administration

May 2011

Onset of allergy

July 2011

A skin biopsy and blood tests confirmed an allergy

24 October 2011

Admission to our hospital

14 December 2011

Liraglutide was additionally started

21 March 2012

Insulin discontinued

April 2012

The symptoms of insulin allergy almost disappeared