Cytomegalovirus esophagitis developing during chemoradiotherapy for esophageal cancer: two case reports

Table 2 Clinical features

Case	At diagnosis						Antiviral therapy	Response to treatment
Case	Intranuclear inclusions	CMV antigenemia	Endoscopic findings	WBC^a (/μL)	Lymphocytes^a (/μL)	CRP^b (mg/dL)	Antiviral therapy	Symptoms	Intranuclear inclusions	CMV antigenemia
1							GCV, VGCV
2	+	+	Ulcer, white base	2200	391	1.99	GCV, VGCV	Improved	Undetected	-

Clinical features at diagnosis of CMV esophagitis and after treatment with antiviral drugs. Low lymphocyte counts at diagnosis of CMV esophagitis are shown. The intranuclear inclusions disappeared, and the test for CMV antigenemia also became negative after the treatment
Abbreviations: CMV cytomegalovirus, WBC white blood cell, CRP C-reactive protein, GCV ganciclovir, VGCV valganciclovir
^aThe nadir WBC and lymphocyte counts before the diagnosis of CMV infection
^bSerum CRP was measured at diagnosis of CMV esophagitis

ISSN: 1752-1947