Skip to main content

Table 1 Clinical and histopathological differential diagnosis of traumatic neuroma versus other neurogenic tumors

From: A diffuse traumatic neuroma in the palate: a case report

  Clinical features Histopathological features
Traumatic neuroma Symptomatic (anesthesia, dysesthesia, and pain), solitary Many nerve bundles, fibrous connective tissue background containing inflammatory cells
Mucosal neuroma Asymptomatic, typically multiple, associated with multiple endocrine neoplasia type 2B Many nerve bundles, normal or loose fibrous connective tissue background without inflammatory cells
Neurofibroma Asymptomatic, solitary, or multiple Nuclei with wavy or serpiginous prolife, fibrous connective tissue background containing mast cells
Palisading neuroma Asymptomatic, solitary Circumscribe, spindle cells showing palisading arrangement
Neurovascular hamartoma Asymptomatic, solitary Many nerve bundles containing vessels, fibrous connective tissue background without inflammatory cells