Fig. 1

Multimodal imaging: matched transverse, postcontrast spin-echo T1-weighted (a), and fluid-attenuated inversion recovery (b) 1.5-T MRI scans, fused MRI/SPECT (c) and ¹¹¹In-pentetreotide SPECT images (d). Transverse postcontrast gradient echo T1-weighted MRI scan (e) showing the location of coronal slices, and three-level coronal T2-weighted fat-suppressed MRI scan (f), fused MRI/SPECT image (g) and [¹¹¹In]-pentetreotide SPECT image (h). MRI scan showed right tortuous optic nerve enlargement (b, dotted arrow), with a peripherally increased signal on fluid-attenuated inversion recovery (b, dotted arrow) and on coronal T2-weighted fat-suppressed sequences (f, dotted arrow). Therefore, uniform contrast enhancement (a and e, solid arrows) affected the last third of the nerve corresponding to an intense [¹¹¹In]-pentetreotide uptake (d and h). The asterisk (*) shows the physiological uptake of [¹¹¹In]-pentetreotide in the pituitary (c and d)