Parameter (reference range) | Admission (day 0) | Postplasmapheresis (day 5) | Initiation of eculizumab (6 weeks after) |
---|---|---|---|
WBC, 109/L | 12 | 7.2 | 5.3 |
Hb, g/dl | 9.1 | 8.2 | 8.0 |
Platelets, 109/L | 150 | 219 | 202 |
Serum Na+, mEq/L | 142 | 135 | 130 |
Serum K+, mEq/L | 4.4 | 5.5 | 5.6 |
Serum bicarbonate, mEq/L | 7 | 26 | 27 |
BUN, mg/dl | 33 | 34 | 66 |
Creatinine, mg/dl | 3.4 | 3.6 | 5.6 |
Glucose, mg/dl | 520 | – | – |
Indirect bilirubin, mg/dl (0.2–0.8) | 1.7 | 0.7 | – |
LDH, IU/L | 1700 | 763 | – |
Haptoglobin, mg/dl (43–212) | <15 | – | – |
pH | 7.33 | – | – |
Anion gap | 20 | – | – |
β-Hydroxybutyrate, mmol/L (0.02–0.27) | 1.21 | – | – |
ADAMTS13 | 81 % | – | – |
Schistocytes | Present | None | – |
Urinalysis | Â | Â | Â |
 pH | 6.0 |  |  |
 Protein, mg/dl | >300 |  |  |
 Glucose, mg/dl | >1000 | – | – |
 RBC | 25–30/HPF |  |  |
 WBC | 0–3/HPF |  |  |
 Granular case | 5–10/HPF |  |  |