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Table 1 FIGO 2000 risk factor scoring system for gestational trophoblastic neoplasia

From: Methotrexate and actinomycin D chemotherapy in a patient with porphyria: a case report

Prognostic factors

Score

 

0

1

2

4

Age (years)

<40

≥40

  

Antecedent pregnancy

Mole

Abortion

Term

 

Interval from index pregnancy (months)

<4

4–7

7–13

>13

Pretreatment serum hCG (IU/mL)

<103

103–104

104–105

>105

Largest tumor size (including the uterus) (cm)

<3

3−5

≥5

 

Metastatic site

Lung

Spleen, kidney

Gastrointestinal tract

Liver, brain

Number of metastases

1−4

5−8

>8

Previous failed chemotherapy

Single drug

≥2 drugs

  1. Total score: ≤6, low risk; >7, high risk
  2. FIGO International Federation of Gynecology and Obstetrics, hCG human chorionic gonadotropin, IU international unit