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Table 1 Apparatus and laboratory findings during the observation period after ibogaine intoxication

From: “Herbal seizures” – atypical symptoms after ibogaine intoxication: a case report

Type of analysis

Day 1

Day 2

Day 3

Day 4

Day 5

Month 3

Computed tomography

No pathological findings

 

Magnetic resonance imaging

No pathological findings

 

Electrocardiogram

Sinus tachycardia (>120 beats per minute)/Sinus rhythm

Sinus rhythm

Sinus rhythm 55 beats per minute; QTc: 100 %

 

Electroencephalogram

 

Irregular alpha rhythm, significant portion of diffuse theta waves, no focal slowing, no epileptiform discharges

Regular alpha rhythm, no focal slowing, no epileptiform discharges

Laboratory findings

Reference values

White blood cell count (×103/μl)

11.7

10.6

6.2

5.1

4.4

4.0–9.4

Platelet count (×103/μl)

248

164

136

127

176

150–440

Lymphocyte count (%)

5.8

11.7

25

29.4

28.0

25–40

Neutrophil count (%)

87.8

79.2

62.4

59.9

58.8

50–75

Creatinine (mg/dl)

1.24

0.84

0.75

0.79

0.76

<1.2

Creatine-kinase (U/l)

370

234

194

<190

C-reactive protein (mg/l)

0.69

0.71

0.39

0.35

0.0–0.5

Carbohydrate-deficient transferrin (%)

1.59

<2.6

Ibogaine concentration in hair sample (pg/mg)

  

22

  

Noribogaine concentration in hair sample (pg/mg)

  

70

  

Noribogaine concentration in urine sample (ng/mg)

  

9.2

  

  1. Pathological findings are marked in bold. All other routine parameters (for example liver enzymes, electrolytes, coagulation status, triglycerides, cholesterol, thyroid-stimulating hormone, free triiodothyronine, and free thyroxine), as well as the screening for drugs in the patient’s urine (benzodiazepine, amphetamine, morphine/opiate/heroin, barbiturates, ecstasy/3,4-methylenedioxy-methamphetamine, methadone, cocaine metabolites, methamphetamine, tetrahydrocannabinol, fentanyl, tricyclic antidepressants, buprenorphine), and in the serum (barbiturates, benzodiazepine, tricyclic antidepressants) showed no pathological findings