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Fig. 3 | Journal of Medical Case Reports

Fig. 3

From: Metastasized pancreatic neuroendocrine tumor in a teenage girl: a case report

Fig. 3

Histopathological findings. Microscopic aspects of primary tumor (a) and liver metastasis (b through f). As shown in hematoxylin and eosin-stained sections (a,b), the tumor displays an organoid growth pattern with predominant trabecular formations of atypical epithelial cells. Nuclei show only little to moderate pleomorphism, and the cytoplasm is well formed and sometimes contains vacuoles. On immunohistochemical examination, tumor cells show positivity for the neuroendocrine markers chromogranin A (c) and synaptophysin (d). Ki67 staining (e) reveals high proliferative activity. The tumor cells display membranous positivity of the somatostatin receptor 2a (f)

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