From: Neonatal McCune–Albright syndrome with systemic involvement: a case report
Sex | Age | Cushing’s syndrome | Liver disease | Heart disease | Treatment/Outcome | Reference |
---|---|---|---|---|---|---|
F | 37 days | + | Elevated LFTs | Cardiomegaly | Death (heart failure age 132 days) | [11] |
M | 10 months | + | Elevated LFTs, direct hyperbilirubinemia | Cardiomegaly, low ejection fraction, hypertension | Aminoglutethimide and metyrapone until age 2 years. Adrenalectomy at 2-years old. Death from cardiac arrest at age 3 years | [12] |
F | 2 months | + | Elevated LFTs, direct hyperbilirubinemia | Left ventricular hypertrophy | Adrenalectomy at 3 months. Death at age 2 years from anaphylaxis and/or adrenal insufficiency | [12] |
M | 10 weeks | + | Hepatomegaly | Cardiomegaly | NR | [13] |
F | 17 days | + | Elevated LFTs, direct hyperbilirubinemia, hepatomegaly | Left ventricular hypertrophy | Metyrapone. Death from pneumonia at age 4 months | Presented case |