Fig. 4

The first needle biopsy. a The specimen shows marked sinusoidal dilatation with cystic cavity formation (hematoxylin and eosin staining, ×100). b Endothelial cells lining these spaces are flat, and no cellular atypia is identified. Liver cell plates are rather atrophic (hematoxylin and eosin staining, ×400). c Immunostaining shows the endothelium of the portal vein (PV) and the hepatic artery (HA) as positive for CD34, but the sinusoidal endothelium (arrows) is negative (×200). Intracytoplasmic granular staining of hepatocytes is nonspecific