From: Hepatitis B virus reactivation or reinfection in a FEM-PrEP participant: a case report
 | Date | ALT (IU/L) | AST (IU/L) | Hepatitis screen | Other tests (normal range) | Comment |
---|---|---|---|---|---|---|
Screening | 13/08/2009 | 22 | 34 | HBsAg = Negative | Â | Â |
HBsAb = Positive HBsAb Value =11.19IU/L | ||||||
RFU Wk 4a | 21/09/2009 | 17 | 22 | – | – |  |
RFU Wk 12 | 16/11/2009 | 32 | 31 | – | – |  |
RFU Wk 24 | 09/02/2010 | 19 | 27 | – | – |  |
RFU Wk 36 | 07/05/2010 | 48 | 59 | – | – | Grade 1a |
RFU Wk 40 | 02/06/2010 | 117 | 95 | – | – | Grade 2 |
RFU Wk 44 | 02/07/2010 | 1094 | 517 | – | – | Grade 4 |
Unscheduled visit | 09/07/2010 | 1,887 | 1,358 | HBsAg = Positive | LDP = 1,298IU/L (200–500) | Diagnosis: Acute Hepatitis B |
Permanent product withdrawal |  |  | HBeAg = Positive | GGT = 433IU/L (0–35) | ||
HBc IgM = Positive | ALP = 68IU/L (40–120) | |||||
HBsAb = Positive | Total bilirubin = 38μmol/L (0–21) | |||||
HBsAb = 11.92IU/L | Direct bilirubin =20μmol/L (0–7) | |||||
HCV IgM = Negative | Epstein–Barr virus IgM = Negative | |||||
HAV IgM = Negative | Cytomegalovirus IgM = Negative | |||||
RFU Wk 48 | 26/07/2010 | 109 | 41 | HBsAg = Positive | LDP = 485IU/L | Grade 2 |
HBeAg = Negative | ||||||
HBc IgM = Positive | GGT = 178IU/L | |||||
HBsAb =11.39IU/L | ALP = 41IU/L | |||||
HBcAb = Positive | Total bilirubin = 15μmol/L | |||||
HBV VL = 87 cp/mL | Direct bilirubin =3.6μmol/L | |||||
International normalized ratio = 1.1 | ||||||
RFU Wk 52 | 23/08/2010 | 23 | 12 | HBsAg = Negative | LDP = 484IU/L | Resolution of hepatitis B infection |
HBV VL = 40 cp/mL | GGT = 49IU/L | |||||
HBsAb = 11.29IU/L | ALP = 36IU/L | |||||
RFU Wk 56 | 20/09/2010 | 22 | 12 | – | – |  |
Stored screening sample | 12/09/2012 | – | – | HBV-DNA PCR: Undetectable | – | Exclusion of occult Hepatitis B |