Pleural sarcoidosis diagnosed on the basis of an increased CD4/CD8 lymphocyte ratio in pleural effusion fluid: a case report

Table 1 Laboratory findings from an earlier visit to another hospital and first admission to our hospital

Hematology		Serology		Bronchoalveolar lavage analysis
WBC	4470/μl	CRP	0.79mg/dl	Cell numbers 3.5×10⁵/ml
Neu	60.3%	IgG	1893mg/dl	Cell fractionation
Lymphocyte	20.7%	ACE	44.2IU/L	Lymphocyte 33%
Monocyte	10.1%	sIL2R	3710U/ml	Neutrophil 1%
Eosinophil	4.0%	CEA	1.1ng/ml	Macrophage 66%
Basophil	1.2%	Blood gas analysis		CD4/8 13.43
RBC	464×10⁴/μl	pH	7.395	Bacterial culture negative
Hb	14.0g/dl	PaO₂	72.9mmHg	Pleural effusion
Ht	41.8%	PaCO₂	41.3mmHg	pH 7.5
Plt	22.4×10⁴/μl	HCO₃	24.8mmol/L	Specific gravity 1.030
Biochemistry		Pulmonary function test		Rivalta 2+
TP	6.3g/dl	VC	1880ml	Protein 4.3mg/dl
Alb	3.3g/dl	%VC	82.3%	Alb 2.3mg/dl
AST	40IU/L	FEV1.0	1270ml	ADA 50.4IU/L
ALT	29IU/L	FEV1.0%	70%	CEA 0.8ng/ml
ALP	764U/L	PEF	3070mL/second	Cell numbers 882/μl
LDH	183IU/L	V50	1040mL/second	Cell fractionation
Crt	0.65mg/dl	V25	400mL/second	Lymphocyte 98%
FBS	90mg/dl	V50/V25	2.60	Neutrophil 2%
Na	141mEq/L	%DLCO	95.4%	CD4/8 ratio 5.62
K	4.5mEq/L	DLCO/VA	4580mL/minute/mmHg/L	PCR negative for tuberculosis
Cl	104mEq/L			Bacterial culture negative
Ca	9.2mg/dl
IP	3.6mg/dl

ACE angiotensin-converting enzyme, ADA adenosine deaminase, Alb albumin, ALP alkaline phosphatase, ALT alanine aminotransferase, AST aspartate aminotransferase, Ca calcium, CEA carcinoembryonic antigen, Cl chlorine, CRP C-reactive protein, Crt creatinie, DLCO carbon monoxide diffusion capacity, FBS fasting blood sugar, FEV1.0 forced expiratory volume in 1 second, Hb hemoglobin, HCO₃ bicarbonate, Ht hematocrit, IgG immunoglobulin G, IP inorganic phosphorus, LDH lactate dehydrogenase, Na sodium, Neu neutrophil, PaCO₂ partial pressure of carbon dioxide in arterial blood, PaO₂ partial pressure of oxygen in arterial blood, PCR, polymerase chain reaction, PEF peak expiratory flow, Plt platelets, RBC red blood cell, sIL2R soluble interleukin-2 receptor, TP total protein, V50 and 25 expirtatory flow at 50% and 25% of vital capacity, respectively, VA alveolar volume, VC vital capacity, WBC white blood cell

ISSN: 1752-1947