Polytetrafluoroethylene fume–induced pulmonary edema: a case report and review of the literature

Hamaya, Rikuta; Ono, Yuko; Chida, Yasuyuki; Inokuchi, Ryota; Kikuchi, Ken; Tameda, Tadanobu; Tase, Choichiro; Shinohara, Kazuaki

doi:10.1186/s13256-015-0593-9

Table 1 Summary of clinical characteristics of polytetrafluoroethylene fume–induced pulmonary edema ^a

From: Polytetrafluoroethylene fume–induced pulmonary edema: a case report and review of the literature

Patient	Authors	Sex	Age (yr)	Comorbid disease	Smoking	Situation	Overheated temperature (°C)	Exposure time	SIRS	Symptoms	Treatment	Outcome (treatment period)
1	Harris et al. [1]	Male	38	No	N/R	Heating PTFE extruder in an oven at a laboratory	N/R	N/R	Yes	Dyspnea	Absolute rest	Discharged (1 day)
2	Lee et al. [11]	Male	43	No	N/R	Molding PTFE-containing materials at a factory, dayshift worker	>410 to 510	9 hr	Yes	Dyspnea, malaise	Intubation, antibiotics, inotropics	Died (5 hr)
3	Lee et al. [11]	Male	37	No	Yes	Foreman of patient 2, with job different from that of patient 2 (monitoring, cutting and packing)	>410 to 510	9 hr (intermittently exposed)	No	Dyspnea, fever, chest pain, chills, malaise	O₂	Discharged (7 days)
4	Lee et al. [11]	Male	22	No	N/R	Colleague of patient 2, a night shift worker with job different from that of patient 2 (monitoring, cutting and packing)	>410 to 510	9 hr (intermittently exposed)	No	Dyspnea, cough, chest pain	N/R	Discharged (9 days)
5	Robbins et al. [4]	Male	38	No	Yes	Welding PTFE-containing materials at a factory.	>560	3 hr	Yes	Dyspnea, cough, fever, chest pain	O₂, antibiotics	Discharged (3 days)
6	Evans et al. [5]	Male	49	No	Yes	Molding PTFE-containing materials at a factory	740	1 hr	N/A	Dyspnea, cough, fever, throat pain	O₂	Discharged (2 days)
7	Haugtomt et al. [8]	Male	33	No	N/R	Sanding Teflon-coated surface at a factory	N/R	15 min	Yes	Dyspnea, fever, chest pain, blood sputum	Diuretics, antibiotics, dopamine, O₂	Discharged (7 days)
8	Brubaker et al. [6]	Male	N/R	No	Yes	Smoking PTFE-contaminated cigarettes during commute	470 to 812	<10 min	N/A	Dyspnea, cough, chest pain, chills	N/R	Discharged (N/R)
9	Patel et al. [13]	Male	40	No	Yes	Smoking PTFE-contaminated cigarettes in the home	470 to 812	<10 min	Yes	Dyspnea, cough, fever, chills	Albuterol	Discharged (2 days)
10	Tanino et al. [12]	Female	25	No	Yes	Smoking PTFE-contaminated cigarettes in the home	470 to 812	<10 minutes	No	Dyspnea, cough, fever	Steroid	Discharged (10 days)
11	Silver et al. [9]	Male	21	No	Yes	Smoking PTFE-contaminated cigarettes at a factory	470 to 812	<10 min	Yes	Dyspnea, cough, chills, nausea/vomiting	Antibiotics	Discharged (1 day)
12	Strøm et al. [14]	Male	36	No	Yes	Smoking PTFE-contaminated cigarettes in the home	470 to 812	<10 min	Yes	Dyspnea, chills	Antibiotics, O₂	Improved (1 day)
13	Myhre et al. [7]	Male	25	No	Yes	Smoking PTFE-contaminated cigarettes during commute	470 to 812	<10 min	N/A	Dyspnea, chills, cough, headache	N/R	Improved (19 hr)
14	Shimizu et al. [2]	Male	29	No	N/R	Overheating PTFE-coated pan on fire in the home	>391	6 hr	No	Dyspnea, cough	O₂	Discharged (3 days)
15	Toyama et al. [16]	Male	59	OSAS	Yes	Overheating PTFE-coated kitchenware in oven in the home	>391	4 hr	Yes	Fever, throat pain	O₂, diuretics	Discharged (9 days)
16	Son et al. [15]	Male	30	BA	Yes	Overheating PTFE-coated pan on fire in the home	>391	7 hr	No	Dyspnea, cough, fever	Observation	Discharged (6 days)
17	Zanen et al. [10]	Female	26	Wilms’ tumor	No	Overheating PTFE-coated kitchenware in microwave oven in the home	>391	<10 min	Yes	Dyspnea, cough, fever, chest pain	O₂, steroid	Discharged (1 day)
18	Our patient	Male	35	No	Yes	Overheating PTFE coated pan on fire in the home	>391	10 hours	Yes	Dyspnea, cough	NPPV, sivelestat	Discharged (11 days)

^aBA, Bronchial asthma; N/A, Not available; NPPV, Non-invasive positive pressure ventilation; N/R, Not recorded; OSAS, Obstructive sleep apnea syndrome; PTFE, Polytetrafluoroethylene; SIRS, Systemic inflammatory response syndrome.

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