Figure 3

Histopathological analysis of the mediastinal lymphadenopathy in July 2003. The sample thought to be a recurrent lesion revealed a moderately to poorly differentiated adenocarcinoma. The tumor cells with round nuclei, eosinophilic cytoplasm, and distinct cell borders are arranged in sheets and show alveolar or solid growth pattern with some glandular cavity. A large number of tumor cells have mucinous cytoplasm. The histologic examination of the primary lesion, which is diagnosed as a “well-differentiated” adenocarcinoma, is inconsistent with the recurrent lesion. However, inconsistent histological analysis between metastatic and primary tumors often occurs. The primary lesion also contains a sheet-like structure, so there is some consistency in diagnosis of this lesion as a recurrence. Hematoxylin and eosin stain, low power.