Evolution of clinico-laboratory data before and after intravenous immunoglobulin administration (A-F). Open circles correspond to the measured values of the patient. The general time trend for each variable is depicted via fitted Loess curves (in blue), with grey areas showing the 95% confidence interval. The black vertical line indicates the intravenous immunoglobulin treatment event. CRP, C-reactive protein; FCT, Fibrinogen clotting time; PLT, Platelets; WBC, White blood cell count.