TY - STD TI - Awada A, Chan S, Jerusalem GHM, Coleman RE, Huizing MT, Mehdi A, O’Reilly SM, Hamm JT, Barrett-Lee PJ, Cocquyt V, Sidras K, Young DE, Brown M, Zhao C, Hannah L, Masuoka LK, Garcia A, Perez EA, NKTR-102 study Group: Antitumor activity in a randomized phase II study comparing two schedules of NKTR-102 in patients (Pts) with pretreated metastatic breast cancer (MBC) [abstract 1034].J Clin Oncol 2011.,29(Suppl): ID - ref1 ER - TY - JOUR AU - Shigeoka, Y. AU - Itoh, K. AU - Igarashi, T. AU - Ishizawa, K. AU - Saeki, T. AU - Fujii, H. AU - Minami, H. AU - Imoto, S. AU - Sasaki, Y. PY - 2001 DA - 2001// TI - Clinical effect of irinotecan in advanced and metastatic breast cancer patients previously treated with doxorubicin- and docetaxel-containing regimens JO - Jpn J Clin Oncol VL - 31 UR - https://doi.org/10.1093/jjco/hye082 DO - 10.1093/jjco/hye082 ID - Shigeoka2001 ER - TY - JOUR AU - Perez, E. A. AU - Hillman, D. W. AU - Mailliard, J. A. AU - Ingle, J. N. AU - Ryan, J. M. AU - Fitch, T. R. AU - Rowland, K. M. AU - Kardinal, C. G. AU - Krook, J. E. AU - Kugler, J. W. AU - Dakhil, S. R. PY - 2004 DA - 2004// TI - Randomized phase II study of two irinotecan schedules for patients with metastatic breast cancer refractory to an anthracycline, a taxane, or both JO - J Clin Oncol VL - 22 UR - https://doi.org/10.1200/JCO.2004.10.047 DO - 10.1200/JCO.2004.10.047 ID - Perez2004 ER - TY - JOUR AU - Taguchi, T. AU - Tominaga, T. AU - Ogawa, M. AU - Ishida, T. AU - Morimoto, K. AU - Ogawa, N. PY - 1994 DA - 1994// TI - A late phase II study of CPT-11 (irinotecan) in advanced breast cancer. CPT-11 study group on breast cancer JO - Gan To Kagaku Ryoho VL - 21 ID - Taguchi1994 ER - TY - JOUR AU - Bonneterre, J. AU - Pion, J. M. AU - Adenis, A. AU - Tubiana-Hulin, M. AU - Tursz, T. AU - Marty, M. AU - Mathieu-Boue, A. PY - 1993 DA - 1993// TI - A phase II study of a new camptothecin analogue CPT-11 in previously treated advanced breast cancer patients [abstract 179] JO - Proc Am Soc Clin Oncol VL - 12 ID - Bonneterre1993 ER - TY - JOUR AU - Rothenberg, M. L. PY - 2001 DA - 2001// TI - Irinotecan (CPT-11): recent developments and future directions-colorectal cancer and beyond JO - Oncologist VL - 6 UR - https://doi.org/10.1634/theoncologist.6-1-66 DO - 10.1634/theoncologist.6-1-66 ID - Rothenberg2001 ER - TY - JOUR AU - Jameson, G. S. AU - Hamm, J. T. AU - Weiss, G. J. AU - Alemany, C. AU - Anthony, S. AU - Basche, M. AU - Ramanathan, R. K. AU - Borad, M. J. AU - Tibes, R. AU - Cohn, A. AU - Hinshaw, I. AU - Jotte, R. AU - Rosen, L. S. AU - Hoch, U. AU - Eldon, M. A. AU - Medve, R. AU - Schroeder, K. AU - White, E. AU - Von Hoff, D. D. PY - 2013 DA - 2013// TI - A multicenter, phase I, dose-escalation study to assess the safety, tolerability and pharmacokinetics of Etirinotecan Pegol in patients with refractory solid tumors JO - Clin Cancer Res VL - 19 UR - https://doi.org/10.1158/1078-0432.CCR-12-1201 DO - 10.1158/1078-0432.CCR-12-1201 ID - Jameson2013 ER - TY - CHAP AU - Eldon, M. A. AU - Staschen, C. M. AU - Viegas, T. AU - Bentley, M. PY - 2007 DA - 2007// TI - Poster presented at the 2007 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics BT - NKTR-102, a Novel PEGylated-Irinotecan Conjugate, Results in Sustained Tumor Growth Inhibition in Mouse Models of Human Colorectal and Lung Tumors that is Associated with Increased and Sustained Tumor SN38 Exposure PB - Poster number C157 CY - San Francisco, CA, USA ID - Eldon2007 ER - TY - CHAP AU - Persson, H. AU - Antonian, L. AU - Staschen, C. M. AU - Viegas, T. AU - Ren, M. AU - Bentley, M. PY - 2007 DA - 2007// TI - Poster presented at the 2007 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics BT - NKTR-102, a Novel Polyethylene Glycol Conjugate of Irinotecan, has Improved Anti-Tumor Activity in Three Mouse Xenograft Models PB - Poster number C10 CY - San Francisco, CA, USA ID - Persson2007 ER - TY - JOUR AU - Vergote, I. B. AU - Micha, J. P. AU - Pippitt, C. H. AU - Rao, G. G. AU - Spitz, D. L. AU - Reed, N. AU - Dark, G. G. AU - Garcia, A. AU - Maslyar, D. J. AU - Rustin, G. J. PY - 2010 DA - 2010// TI - Phase II study of NKTR-102 in women with platinum-resistant/refractory ovarian cancer [abstract 5013] JO - J Clin Oncol VL - 28 ID - Vergote2010 ER - TY - JOUR AU - Zelek, L. AU - Barthier, S. AU - Riofrio, M. AU - Fizazi, K. AU - Rixe, O. AU - Delord, J. P. AU - Le Cesne, A. AU - Spielmann, M. PY - 2001 DA - 2001// TI - Weekly vinorelbine is an effective palliative regimen after failure with anthracyclines and taxanes in metastatic breast carcinoma JO - Cancer VL - 92 UR - https://doi.org/3.0.CO;2-Q DO - 3.0.CO;2-Q ID - Zelek2001 ER - TY - JOUR AU - Rogers, L. R. AU - Remer, S. E. AU - Tejwani, S. PY - 2004 DA - 2004// TI - Durable response of breast cancer leptomeningeal metastasis to capecitabine monotherapy JO - Neuro Oncol VL - 6 UR - https://doi.org/10.1215/S1152851703000334 DO - 10.1215/S1152851703000334 ID - Rogers2004 ER - TY - JOUR AU - Schmid, P. AU - Akrivakis, K. AU - Flath, B. AU - Grosse, Y. AU - Sezer, O. AU - Mergenthaler, H. G. AU - Possinger, K. PY - 1999 DA - 1999// TI - Phase II trial of gemcitabine as prolonged infusion in metastatic breast cancer JO - Anticancer Drugs VL - 10 UR - https://doi.org/10.1097/00001813-199908000-00001 DO - 10.1097/00001813-199908000-00001 ID - Schmid1999 ER - TY - JOUR AU - Gullo, G. AU - De Giorgi, A. AU - Quinn, C. AU - Ballot, J. AU - Hammond, L. AU - Crown, J. PY - 2014 DA - 2014// TI - Long-term follow up (FU) of patients with durable complete response (DCR) after chemotherapy (CT) and HER2-targeting systemic therapy (HER2-Tx) for HER2+ metastatic breast cancer (MBC) [abstract 641] JO - J Clin Oncol VL - 32 ID - Gullo2014 ER - TY - JOUR AU - Bianchi, G. V. AU - Duca, M. AU - Sica, L. AU - Mariani, G. PY - 2013 DA - 2013// TI - Metastatic breast cancer treated with lapatinib with a prolonged benefit: a case report and a review of therapeutic options available JO - Tumori VL - 99 ID - Bianchi2013 ER - TY - JOUR AU - Foukakis, T. AU - Aström, G. AU - Lindström, L. AU - Hatschek, T. AU - Bergh, J. PY - 2012 DA - 2012// TI - When to order a biopsy to characterise a metastatic relapse in breast cancer JO - Ann Oncol VL - 23 UR - https://doi.org/10.1093/annonc/mds297 DO - 10.1093/annonc/mds297 ID - Foukakis2012 ER - TY - STD TI - The BEACON Study (Breast Cancer Outcomes With NKTR-102): A phase 3 open-label, randomized, multicenter study of NKTR-102 versus treatment of physician’s choice (TPC) in patients with locally recurrent or metastatic breast cancer previously treated with an anthracycline, a taxane and capecitabine. http://clinicaltrials.gov/show/NCT01492101 UR - http://clinicaltrials.gov/show/NCT01492101 ID - ref17 ER -