Serum calcium, phosphate, and intact parathyroid hormone levels in the first 14 weeks of the disease (the period before surgical debridement). The sodium thiosulfate treatment began in week 7 and ended in week 12. During this period, the predialysis calcium levels markedly increased compared with the levels before and after treatment. Paricalcitol (4μg, three times per week) was discontinued in week 9 because hypercalcemia persisted. The dialysate calcium concentration was decreased from 2.5 to 2.2mEq/L, and then to 2.0mEq/L, stepwise (presented as Ca 2.5, Ca 2.2 and Ca 2.0). Sevelamer was used throughout the course of treatment. STS, sodium thiosulfate; Pi, serum phosphate; i-PTH, intact parathyroid hormone.