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Table 2 Results of multichannel impedance-pH monitoring before pucalopride treatment

From: Prucalopride reduces the number of reflux episodes and improves subjective symptoms in gastroesophageal reflux disease: a case series

  Patient 1 Patient 2 Patient 3 Patient 4
MII-pH monitoring before treatment with prucalopride Medication during monitoring: Medication during monitoring: Medication during monitoring: Medication during monitoring:
- Ranitidine 75mg per day - Pantoprazole 40mg per day - Omeprazole 20mg per day - none
Acid reflux time: 1.5% Acid reflux time: 0.3% Acid reflux time: 0.1% Acid reflux time: 2.8%
Overall reflux episodes: 128 Overall reflux episodes: 143 Overall reflux episodes: 96 Overall reflux episodes: 108
Mixed or liquid reflux episodes: 94 Mixed or liquid reflux episodes: 140 Mixed or liquid reflux episodes: 79 Mixed or liquid reflux episodes: 104
Gaseous reflux episodes: 34 Gaseous reflux episodes: 3 Gaseous reflux episodes: 17 Gaseous reflux episodes: 4
Acid reflux episodes: 84 Acid reflux episodes: 15 Acid reflux episodes: 17 Acid reflux episodes: 71
Non- and/or weakly acid reflux episodes: 44 Non- and/or weakly acid reflux episodes: 128 Non- and/or weakly acid reflux episodes: 79 Non- and/or weakly acid reflux episodes: 37
*Scale 0 to 10: 0 = none; 10 = unbearable Subjective symptom scores* Subjective symptom scores* Subjective symptom scores* Subjective symptom scores*
- Heartburn + Regurgitation: 5 - Heartburn + Regurgitation: 7 - Regurgitation: 5 - Heartburn, Globus, Bloating: 9
- Limitation of daily life: 5 - Limitation of daily life: 6 - Limitation of daily life: 5 - Limitation of daily life: 9
  SI: positive for heartburn and regurgitation SI: positive for heartburn and regurgitation SI: positive for regurgitation SI: positive for heartburn, globus and bloating
  1. MII – multichannel impedance monitoring, SI - symptom index.
  2. Subjective symptom score is based on the questionnaire previously described by Becker V et al.[7]. SI, Symptom index.