Table 2 Results of multichannel impedance-pH monitoring before pucalopride treatment

MII-pH monitoring before treatment with prucalopride

Medication during monitoring:

Medication during monitoring:

Medication during monitoring:

Medication during monitoring:

- Ranitidine 75mg per day

- Pantoprazole 40mg per day

- Omeprazole 20mg per day

- none

Acid reflux time:

1.5%

Acid reflux time:

0.3%

Acid reflux time:

0.1%

Acid reflux time:

2.8%

Overall reflux episodes:

128

Overall reflux episodes:

143

Overall reflux episodes:

96

Overall reflux episodes:

108

Mixed or liquid reflux episodes:

94

Mixed or liquid reflux episodes:

140

Mixed or liquid reflux episodes:

79

Mixed or liquid reflux episodes:

104

Gaseous reflux episodes:

34

Gaseous reflux episodes:

3

Gaseous reflux episodes:

17

Gaseous reflux episodes:

4

Acid reflux episodes:

84

Acid reflux episodes:

15

Acid reflux episodes:

17

Acid reflux episodes:

71

Non- and/or weakly acid reflux episodes:

44

Non- and/or weakly acid reflux episodes:

128

Non- and/or weakly acid reflux episodes:

79

Non- and/or weakly acid reflux episodes:

37

*Scale 0 to 10: 0 = none; 10 = unbearable

Subjective symptom scores*

Subjective symptom scores*

Subjective symptom scores*

Subjective symptom scores*

- Heartburn + Regurgitation: 5

- Heartburn + Regurgitation: 7

- Regurgitation: 5

- Heartburn, Globus, Bloating: 9

- Limitation of daily life: 5

- Limitation of daily life: 6

- Limitation of daily life: 5

- Limitation of daily life: 9

SI: positive for heartburn and regurgitation

SI: positive for heartburn and regurgitation

SI: positive for regurgitation

SI: positive for heartburn, globus and bloating