Table 1 Magnetic resonance imaging and clinical findings of biopsy-proven cases of primary angiitis of the central nervous system
Reference | Age (y)/sex | Symptoms | MRI findings | Location of abnormalities | MRI with gadolinium contrast description | Biopsy |
|---|---|---|---|---|---|---|
Shoemaker et al.[13] | 45/M | Dysesthesias, loss of sensation, gait imbalance | T2 focal areas of high signal | Brainstem, cerebellum, cerebral white matter | Multiple focal areas of enhancement, some were linear | Small arteries infiltrated by lymphocytes, macrophages, neutrophils |
Campi et al. [14] | 50/M | Progressive severe paraparesis | Small punctate T2 hyperintensities | Subcortical, supra- and infratentorial white matter | Punctate contrast enhancement | Inflammation of small vessels with lymphocytes and granulocytes |
Campi et al. [14] | 29/F | Headache, diplopia, ataxia | Small high signal foci on T2 images | Supratentorial white matter | Enhancement of Virchow-Robin spaces | Vasculitis of small parenchymal vessels, fibrinoid necrosis |
Hassan et al. [15] | 38/F | Tremor, gait ataxia, incoherent mentation | T2 white matter hyperintensities | Diffuse | Contrast enhancement in a linear radiating fashion | Perivascular inflammation with T cells, B cells and macrophages |
Patient in this report | 47/M | Tremor, headache, gait imbalance | T2 with diffuse hyperintensity | Centrum semiovale and corona radiata | Bilateral linear enhancements in a radiating fashion | Perivascular non-caseating granulomas |