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Table 3 Cases with myasthenia gravis associated with antiphospholipid syndrome

From: Double seronegative myasthenia gravis with antiphospholipid syndrome: a case report

Case Manifestations of Manifestations of Laboratory findings
  myasthenia gravis antiphospholipid syndrome  
Kaji et al.[13] Woman, 47 Began after thymectomy Prolonged aPTT, thrombocytopenia, anti-β2 glycoprotein-I antibody positive
Diplopia, weakness of arms and legs with prolonged exertion Phlebothrombosis of the lower extremity, multiple strokes Anti AChR-Ab 61nmol/L (N <0.2nmol/L)
Shoenfeld et al.[14] Woman, 32 Began after thymectomy Abortion, stroke and spleen artery thrombosis Anticardiolipin antibodies positive
Hand weakness Anti AChR-Ab positive
Watanabe et al.[15] Woman, 40 Diplopia, bilateral ptosis Abortion, pulmonary embolism Prolonged aPTT, thrombocytopenia, anti-β2 glycoprotein-I antibody and lupus anticoagulant positive
Anti AChR-Ab 490nmol/L (N <0.2nmol/L)
Present case Woman, 42 Fluctuating faciobulbar weakness Abortions Prolonged aPTT, anti-β2 glycoprotein-I and anticardiolipin antibody positive
Antinuclear-Ab positive
Anti AChR-Ab, MuSK-Ab, titin-Ab negative
  1. Abbreviations: Ab, antibodies; AChR, acetylcholine receptor; APTT, activated partial thromboplastin time; MuSK, muscle-specific receptor tyrosine-kinase.