Figure 3

Immunohistochemical analysis for the markers of endothelial cells, mesenchymal cells and cell proliferation in the specimen. In the hemangioma portion of the lesion, the endothelial cell markers, CD34 and CD31, and the mesenchymal cell marker, vimentin, were strongly observed, but the cell proliferating marker, Ki-67, was negatively expressed in the newly developed vascular vessels. However, in the PG portion, CD34 was almost negatively detected, whereas vimentin and Ki-67 were highly detected in the fibroblast-like tumor cells. Scale bar = 100μm. CD31, Cluster of differentiation 31 (platelet endothelial cell adhesion molecule); CD34, Cluster of differentiation 34; Ki-67, MKI67; PG, pyogenic granuloma.