TY - JOUR AU - Wardle, A. J. AU - Tulloh, R. M. PY - 2013 DA - 2013// TI - Paediatric pulmonary hypertension and sildenafil: current practice and controversies JO - Arch Dis Child Educ Pract Ed VL - 98 UR - https://doi.org/10.1136/archdischild-2013-303981 DO - 10.1136/archdischild-2013-303981 ID - Wardle2013 ER - TY - JOUR AU - Nichols, D. J. AU - Muirhead, G. J. AU - Harness, J. A. PY - 2002 DA - 2002// TI - Pharmacokinetics of sildenafil after single oral doses in healthy male subjects: absolute bioavailability, food effects and dose proportionality JO - Br J Clin Pharmacol VL - 53 UR - https://doi.org/10.1046/j.0306-5251.2001.00027.x DO - 10.1046/j.0306-5251.2001.00027.x ID - Nichols2002 ER - TY - JOUR AU - Ahsman, M. J. AU - Witjes, B. C. AU - Wildschut, E. D. AU - Sluiter, I. AU - Vulto, A. G. AU - Tibboel, D. AU - Mathot, R. A. PY - 2010 DA - 2010// TI - Sildenafil exposure in neonates with pulmonary hypertension after administration via a nasogastric tube JO - Arch Dis Child Fetal Neonatal Ed VL - 95 UR - https://doi.org/10.1136/adc.2009.168336 DO - 10.1136/adc.2009.168336 ID - Ahsman2010 ER - TY - JOUR AU - Apitz, C. AU - Reyes, J. T. AU - Holtby, H. AU - Humpl, T. AU - Redington, A. N. PY - 2010 DA - 2010// TI - Pharmacokinetic and hemodynamic responses to oral sildenafil during invasive testing in children with pulmonary hypertension JO - J Am Coll Cardiol VL - 55 UR - https://doi.org/10.1016/j.jacc.2009.11.065 DO - 10.1016/j.jacc.2009.11.065 ID - Apitz2010 ER - TY - JOUR AU - Lammers, A. E. AU - Haworth, S. G. AU - Pierce, C. M. PY - 2006 DA - 2006// TI - Intravenous sildenafil as an effective treatment of pulmonary hypertensive crises during acute intestinal malabsorption JO - Cardiol Young VL - 16 UR - https://doi.org/10.1017/S1047951105002155 DO - 10.1017/S1047951105002155 ID - Lammers2006 ER - TY - JOUR AU - Fraisse, A. AU - Butrous, G. AU - Taylor, M. B. AU - Oakes, M. AU - Dilleen, M. AU - Wessel, D. L. PY - 2011 DA - 2011// TI - Intravenous sildenafil for postoperative pulmonary hypertension in children with congenital heart disease JO - Intensive Care Med VL - 37 UR - https://doi.org/10.1007/s00134-010-2065-4 DO - 10.1007/s00134-010-2065-4 ID - Fraisse2011 ER - TY - JOUR AU - Yin, J. AU - Kukucka, M. AU - Hoffmann, J. AU - Sterner-Kock, A. AU - Burhenne, J. AU - Haefeli, W. E. AU - Kuppe, H. AU - Kuebler, W. M. PY - 2011 DA - 2011// TI - Sildenafil preserves lung endothelial function and prevents pulmonary vascular remodeling in a rat model of diastolic heart failure JO - Circ Heart Fail VL - 4 UR - https://doi.org/10.1161/CIRCHEARTFAILURE.110.957050 DO - 10.1161/CIRCHEARTFAILURE.110.957050 ID - Yin2011 ER - TY - JOUR AU - Nahata, M. C. AU - Morosco, R. S. AU - Brady, M. T. PY - 2006 DA - 2006// TI - Extemporaneous sildenafil citrate oral suspensions for the treatment of pulmonary hypertension in children JO - Am J Health Syst Pharm VL - 63 UR - https://doi.org/10.2146/ajhp050208 DO - 10.2146/ajhp050208 ID - Nahata2006 ER - TY - JOUR AU - Barst, R. J. AU - Ivy, D. D. AU - Gaitan, G. AU - Szatmari, A. AU - Rudzinski, A. AU - Garcia, A. E. AU - Sastry, B. K. AU - Pulido, T. AU - Layton, G. R. AU - Serdarevic-Pehar, M. AU - Wessel, D. L. PY - 2012 DA - 2012// TI - A randomized, double-blind, placebo-controlled, dose-ranging study of oral sildenafil citrate in treatment-naive children with pulmonary arterial hypertension JO - Circulation VL - 125 UR - https://doi.org/10.1161/CIRCULATIONAHA.110.016667 DO - 10.1161/CIRCULATIONAHA.110.016667 ID - Barst2012 ER - TY - BOOK PY - 2012 DA - 2012// TI - FDA Drug Safety Communication: FDA recommends against use of Revatio (sildenafil) in children with pulmonary hypertension PB - FDA CY - Silver Spring, MD ID - ref10 ER - TY - JOUR AU - Abman, S. H. AU - Kinsella, J. P. AU - Rosenzweig, E. B. AU - Krishnan, U. AU - Kulik, T. AU - Mullen, M. AU - Wessel, D. L. AU - Steinhorn, R. AU - Adatia, I. AU - Hanna, B. AU - Feinstein, J. AU - Fineman, J. AU - Raj, U. AU - Humpl, T. PY - 2013 DA - 2013// TI - Implications of the U.S. Food and Drug Administration warning against the use of sildenafil for the treatment of pediatric pulmonary hypertension JO - Am J Respir Crit Care Med VL - 187 UR - https://doi.org/10.1164/rccm.201210-1928PP DO - 10.1164/rccm.201210-1928PP ID - Abman2013 ER - TY - JOUR AU - De Siati, M. AU - Saugo, M. AU - Franzolin, N. PY - 2003 DA - 2003// TI - The start of pharmacological activity after sublingual administration of sildenafil citrate in 30 patients affected by erectile dysfunction JO - Arch Ital Urol Androl VL - 75 ID - De Siati2003 ER - TY - JOUR AU - Freitas, A. F. AU - Bacal, F. AU - Oliveira, J. L. AU - Santos, R. H. B. AU - Moreira, L. F. P. AU - Silva, C. R. AU - Mangini, S. AU - Carneiro, R. M. D. AU - Fiorelli, A. I. AU - Bocchi, E. A. PY - 2009 DA - 2009// TI - [Impact of sublingual sildenafil on pulmonary hypertension in patients with heart failure] [in English Portuguese and Spanish] JO - Arq Bras Cardiol VL - 92 UR - https://doi.org/10.1590/S0066-782X2009000200008 DO - 10.1590/S0066-782X2009000200008 ID - Freitas2009 ER - TY - JOUR AU - Zayed, R. AU - Kamel, A. O. AU - Shukr, M. AU - El-Shamy, A. PY - 2012 DA - 2012// TI - An in vitro and in vivo comparative study of directly compressed solid dispersions and freeze dried sildenafil citrate sublingual tablets for management of pulmonary arterial hypertension JO - Acta Pharm VL - 62 UR - https://doi.org/10.2478/v10007-012-0027-9 DO - 10.2478/v10007-012-0027-9 ID - Zayed2012 ER - TY - JOUR AU - Muirhead, G. J. AU - Wulff, M. B. AU - Fielding, A. AU - Kleinermans, D. AU - Buss, N. PY - 2000 DA - 2000// TI - Pharmacokinetic interactions between sildenafil and saquinavir/ritonavir JO - Br J Clin Pharmacol VL - 50 UR - https://doi.org/10.1046/j.1365-2125.2000.00245.x DO - 10.1046/j.1365-2125.2000.00245.x ID - Muirhead2000 ER - TY - JOUR AU - Muirhead, G. J. AU - Wilner, K. AU - Colburn, W. AU - Haug-Pihale, G. AU - Rouviex, B. PY - 2002 DA - 2002// TI - The effects of age and renal and hepatic impairment on the pharmacokinetics of sildenafil JO - Br J Clin Pharmacol VL - 53 UR - https://doi.org/10.1046/j.0306-5251.2001.00029.x DO - 10.1046/j.0306-5251.2001.00029.x ID - Muirhead2002 ER - TY - JOUR AU - de Wildt, S. N. PY - 2011 DA - 2011// TI - Profound changes in drug metabolism enzymes and possible effects on drug therapy in neonates and children JO - Expert Opin Drug Metab Toxicol VL - 7 UR - https://doi.org/10.1517/17425255.2011.577739 DO - 10.1517/17425255.2011.577739 ID - de Wildt2011 ER - TY - JOUR AU - Saussele, T. AU - Burk, O. AU - Blievernicht, J. K. AU - Klein, K. AU - Nussler, A. AU - Nussler, N. AU - Hengstler, J. G. AU - Eichelbaum, M. AU - Schwab, M. AU - Zanger, U. M. PY - 2007 DA - 2007// TI - Selective induction of human hepatic cytochromes P450 2B6 and 3A4 by metamizole JO - Clin Pharmacol Ther VL - 82 UR - https://doi.org/10.1038/sj.clpt.6100138 DO - 10.1038/sj.clpt.6100138 ID - Saussele2007 ER - TY - JOUR AU - Hyland, R. AU - Roe, E. G. AU - Jones, B. C. AU - Smith, D. A. PY - 2001 DA - 2001// TI - Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil JO - Br J Clin Pharmacol VL - 51 UR - https://doi.org/10.1046/j.1365-2125.2001.00318.x DO - 10.1046/j.1365-2125.2001.00318.x ID - Hyland2001 ER - TY - JOUR AU - Karatza, A. A. AU - Bush, A. AU - Magee, A. G. PY - 2005 DA - 2005// TI - Safety and efficacy of sildenafil therapy in children with pulmonary hypertension JO - Int J Cardiol VL - 100 UR - https://doi.org/10.1016/j.ijcard.2004.09.002 DO - 10.1016/j.ijcard.2004.09.002 ID - Karatza2005 ER -