Figure 4

Histopathology of the lymph node. (A) Multiple fragmented condensed nuclei (apoptotic bodies) are seen in the eosinophilic degenerated giant cell (arrow) with fibrotic configuration. Hematoxylin and eosin stain (under×40 magnification objective). (B) Two eosinophilic degenerated giant cells (blue and black arrows) showing indistinct nuclear configurations, which are probably in the advanced stage of degeneration. One cell (blue arrow) shows fibrotic configuration. Yellow arrows indicate relatively intact giant cells. Hematoxylin and eosin stain (under×20 magnification objective). (C) Black arrows indicate three eosinophilic homogenous degenerated substances (hyaline-like degeneration) with fibrotic configuration. Nuclear remnants are barely visible. Morphological transition from degenerating/degenerated giant cells to hyaline-like degeneration is shown. Hematoxylin and eosin stain (under×20 magnification objective). (D) A degenerating giant cell (black arrow) and a degenerated giant cell (blue arrow) showing increased periodic acid–Schiff stainability. Periodic acid–Schiff stain (under×20 magnification objective).