Figure 4

Expression of high mobility group box chromosomal protein 1 in the hepatic tissues. (A) High mobility group box chromosomal protein 1 messenger ribonucleic acid levels were determined by reverse transcriptase polymerase chain reaction. The high mobility group box chromosomal protein 1 messenger ribonucleic acid levels in the affected tissues of the patient with hepatic actinomycosis were significantly higher than those in the control and hepatocellular carcinoma tissues (0.82 vs. 0.15±0.02 and 0.51±0.07, respectively). (B) Total protein was extracted from hepatic tissues and high mobility group box chromosomal protein 1 content was detected by western blot. The high mobility group box chromosomal protein 1 content in the affected tissues of the patient with hepatic actinomycosis was significantly higher than that of the control and hepatocellular carcinoma tissues (0.87 versus 0.32±0.09 and 0.55±0.07, respectively). HMGB1, high mobility group box chromosomal protein 1; HCC, hepatocellular carcinoma; mRNA, messenger ribonucleic acid; bp, base pairs.