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Table 2 Summary of reported cases of adult pneumococcal meningitis with normal cerebrospinal fluid cell counts

From: Adult pneumococcal meningitis presenting with normocellular cerebrospinal fluid: two case reports

Case/authors

Age/sex

(years)

Underlying condition

Other site of infection

Cerebrospinal fluid examination

Antibiotics

Outcome

Cell/PMN (/μL)

Glucose (mg/dL)

Protein (mg/dL)

Gram stain

1/Fishbein et al.[4]

33/M

Hodgkin’s disease

None

0/0

1

685

GPC

CET→CP

Death

2/Fishbein et al.[4]

57/M

Alcoholism

Pneumonia

1/0

130

97

Negative

PCG

Survival

3/Fishbein et al.[4]

86/M

None

Pneumonia

0/0

221

40

GPC

PCG

Death

4/Ris et al.[5]

50/F

None

Pneumonia

0/0

95

21

Negative

CTX→PCG

Survival

5/Zenebe [6]

18/M

ND

None

0/0

4

300

GPC

None

Death

6/Uchihara et al.[7]

52/M

None

None

6/2

71

26

ND

CMX→PCG→ABPC+RFP

Survival

7/Montassier et al.[8]

60/F

None

None

0/0

70

39

Negative

CTRX

Survival

8/Alvarez et al.[9]

37/M

None

None

1/ND

52

47

Negative

VCM+CFPM+MNZ→CTRX

Survival

9/present case 1

34/F

Splenectomy

None

2/1

56

40

GPC

CTX+VCM→CTX

Survival

10/present case 2

62/M

None

Pneumonia

1/0

8

125

GPC

None

Death

  1. ABPC Ampicillin, CET Cephalothin, CFPM Cefepime, CMX Cefmenoxime, CP Chloramphenicol, CTRX Ceftriaxone, CTX Cefotaxime, F Female, GPC Gram-positive cocci, M Male, MNZ Metronidazole, ND Not described, PCG Penicillin G, PMN Polymorphonuclear leukocytes, RFP Rifampin, VCM Vancomycin.