Skip to main content

Advertisement

Table 2 Classical Bartter syndrome with growth hormone deficiency: cases from the literature

From: Classic Bartter syndrome complicated with profound growth hormone deficiency: a case report

Reference Age, years Sex Mutation GH peak (μg/L) to stimulants IGF-1 (ng/mL)
[9] 5 M IVS2-1G > C/W610X 9.3 (GLC), 8.0 (CLN), 8.2 (l-DOPA), 38.0 (ARG) Not determined
[10] 8 F Not determined 2.9 (INS), 2.0 (CLN), 6.9 (GRF) 122.1
[7] 10 M Not determined 3.20 (INS), 3.20 (l-DOPA) 25
[8] 10 F Not determined 0.70 (l-DOPA), 1.96 (CLN) 41.5
11 M Not determined 4.70 (l-DOPA), 1.79 (CLN) 39.7
11 M Not determined 0.50 (l-DOPA), 4.49 (CLN) 38.3
[2] 11 M ΔExon1-6/ΔExon1-6 7.6 (ARG) Low
14 M ΔExon1-19/ΔExon1-19 2.4 (ARG), 8.4 (GRF) Low
[3] 22 F Not determined Absence (INS), 8.0 (ARG) Not determined
Present case 14 M ΔL130/ΔExon1-3 0.15 (INS), 0.39 (ARG) 80
  1. ARG arginine, CLN clonidine, l -DOPA l-3,4-dihydroxyphenylalanine, GH growth hormone, GLC glucagon, GRF, growth hormone releasing factor, IGF-1 insulin-like growth factor 1, INS insulin.