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Figure 5 | Journal of Medical Case Reports

Figure 5

From: A hepatic sclerosed hemangioma with significant morphological change over a period of 10 years: a case report

Figure 5

Electron microscopic findings. a: Electron micrograph shows a hyalinized lesion. Cells resembling histiocytes, fibroblast-like cells, and remnant endothelial cells derived from sclerosed hemangioma are observed. White arrowheads denote histiocytes or mast cells. Bar denotes 5μm. b: At high magnification, a remnant endothelial cell contains a few micropinocytic vesicles and caveolae, but numerous cytoplasmic filaments. White arrowheads denote caveolae. Bar denotes 500nm. c: Residual hemangioma is composed of numerous caverns in various shapes and sizes. The caverns form a labyrinth, communicating with each other. They are lined by spindle-shaped endothelial cells. Bar denotes 5μm. d: At high magnification, residual endothelial cells are composed of many micropinocytic vesicles or caveolae on the luminal surface. Residual cavernous hemangioma contains numerous cytoplasmic filaments. White arrowheads denote caveolae and vesicles. Bar denotes 500nm. Uranyl acetate and lead citrate staining.

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