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Figure 4 | Journal of Medical Case Reports

Figure 4

From: A hepatic sclerosed hemangioma with significant morphological change over a period of 10 years: a case report

Figure 4

Histologic features of the sclerosed hemangioma nodule. a: A hyalinized mass is distinguished from the surrounding normal liver tissue (hematoxylin and eosin staining). b:The mass is composed of collapsed vascular spaces on a rich paucicellular fibrous stroma. Sclerosis is highlighted by Masson’s trichrome stain. c: The vascular spaces are clearly identified by immunohistochemistry for the endothelial marker CD34. d: The vascular and cavernous hemangioma spaces are identified by immunohistochemistry for the vascular smooth muscle cell marker, alpha smooth muscle actin. Asterisks denote sclerosed portion.

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