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Table 2 T cell subset counts in patients with juvenile idiopathic arthritis (JIA) and healthy donors (HD)

From: Increased replication of CD4+ naive T cells and changes in T cell homeostasis in a case of acute exacerbation of juvenile idiopathic arthritis: a case comparison study

 

Patient with JIA with acute exacerbation/follow-up

JIA group (n=6)

JIA follow-up (n=6)

HD (n=6)

CD3+

1.1/1.3

1.73±0.68 (1.60; 1.10 to 2.80)

1.04±0.49 (0.98; 0.51 to 1.72)++

2.18±0.36 (2.0; 1.90 to 2.70)

CD3+HLA-DR+

0.06/0.03

0.09±0.01 (0.09; 0.08 to 0.11)

0.09±0.05 (0.11; 0.03 to 0.16)

0.13±0.03 (0.12; 0.11 to 0.19)xx

CD3+CD4+

0.72/0.93

0.94±0.48 (0.79; 0.55 to 1.83)

0.59±0.31 (0.62; 0.24 to 0.96)++

1.31±0.35 (1.24; 0.88 to 1.84)

CD4+CD25+CD62L+

0.12/0.04

0.19±0.18 (0.15; 0.03 to 0.52)

0.14±0.09 (0.13; 0.05 to 0.26)

0.25±0.08 (0.23; 0.15 to 0.35)

CD4+CD28+

0.20/0.31

0.90±0.46 (0.76; 0.53 to 1.73)***

0.57±0.29 (0.62; 0.23 to 0.90)+++

1.27±0.34 (1.22; 0.84 to 1.78)xx

CD4+CD28+CD45RA+

0.15/0.16

0.33±0.24 (0.25; 0.001 to 0.62)

0.31±0.15 (0.35; 0.13 to 0.46)++

0.49±0.012 (0.45; 0.34 to 0.63)xx

CD4+CD45RA+CD62L+

0.22/0.04

0.39±0.24 (0.43; 0.001 to 1.14)

0.19±0.08 (0.19; 0.09 to 0.28)

0.34±0.32 (0.16, 0.19 to 0.61)

CD4+CD45RO+

0.12/0.15

0.08±0.07 (0.06; 0.01 to 0.22)

0.22±0.13 (0.23; 0.07 to 0.38)

0.15±0.11 (0.17; 0.001 to 0.29)

CD3+CD8+

0.34/0.37

0.50±0.19 (0.49; 0.27 to 0.73)

0.41±0.18 (0.37; 0.21 to 0.65)++

0.78±0.14 (0.76; 0.63 to 0.96)

CD8+CD28+

0.28/0.32

0.41±0.16 (0.41; 0.18 to 0.64)

0.31±0.15 (0.26; 0.17 to 0.51)++

0.61±0.11 (0.64; 0.47 to 0.75)

CD8+CD28+CD45RA+

0.30/0.25

0.57±0.51 (0.43; 0.01 to 1.44)

0.29±0.13 (0.27; 0.16 to 0.47)+

0.66±0.24 (0.63; 0.41 to 1.06)

CD8+CD45RA+CD62L+

0.07/0.09

0.31±0.25 (0.20; 0.05 to 0.53)***

0.19±0.07 (0.16; 0.12 to 0.29)

0.32±0.29 (0.13; 0.19 to 0.52)

CD8+CD45RO+

0.38/0.90

0.23±0.12 (0.23; 0.03 to 0.41)**

0.70±0.30 (0.61; 0.30 to 1.13)

0.41±0.25 (0.42; 0.001 to 0.69)

  1. Total counts ×103 cells/μL are given as mean±standard deviation (median; range). Significant differences between patients with JIA (JIA group) and JIA follow-up are indicated with **p<0.025, ***p<0.01. Significant differences between JIA follow-up and HD are indicated with +p<0.05, ++p<0.025, +++p<0.01. Significant differences between JIA group and HD are indicated with xxp<0.025.