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Table 1 Summary of the reported cases of primary synovial sarcoma in the gastrointestinal tract

From: Monophasic synovial sarcoma presenting as a primary ileal mass: a case report and review of the literature

Author, year, reference Location Presenting symptoms Age, years Gender Size, cm Gross features Histologic type Translocation Treatment Status and follow-up, months
Palmer et al. 1983 [16] Esophagus Dysphagia 75 F 2.5 Polypoid Biphasic - S+Rad DOD, 24
Amr et al. 1984 [17] Esophagus Dysphagia 25 M 5 Polypoid Biphasic - S+Rad AWOD, 36
Bloch et al., 1987 [18] Esophagus Dysphagia, dyspnea 15 M 7 Polypoid Biphasic - S+Rad AWOD, 36
Pulpiero et al., 1988 [19] Esophagus   24 M    Biphasic - S NR
Caldwell et al., 1991 [20] Esophagus   29 F    NR - S+Rad+Chemo AWOD, 195
Perch et al., 1991 [21] Esophagus   15 M    Biphasic - S+Rad AWOD, 5 to 6 years after surgery
Antón-Pacheco et al., 1996 [22] Esophagus Dysphagia, weight loss 14 F 7 Polypoid Biphasic - S+Chemo+Rad AWOD, 30
Habu S et al. 1998 [23] Esophagus Sensation of something stuck in the throat 20 M 8 Polypoid Biphasic - S+Chemo+Rad AWOD, 20
Bonavina et al., 1998 [24] Esophagus Achalasia 63 F   Polypoid NR - - -
Billings et al., 2000 [25] Gastroesophageal junction Incidental finding for pyloric stenosis 47 M 5.2 Polypoid Biphasic t(X; 18) S AWOD, 21
Billings et al., 2000 [25] Stomach Abdominal pain, nausea, vomiting and rectal bleeding 55 F 16 Spherical, intramural Biphasic and PDSS t(X; 18) S DOD, 6
Chan et al., 2004 [26] Jejunum Epigastric pain, vomiting and fever 28 M 15 Polypoid, intramural Monophasic t(X; 18), SSX2 S DOD, 1
Butori et al., 2006 [27] Esophagus Dysphagia 72 F 11 Polypoid Biphasic t(X; 18) S+Chemo 6
Akhunji et al., 2007 [28] Stomach Epigastric pain 42 M 11   Biphasic t(X; 18) S+Chemo DOD, 24
Parfitt et al., 2007 [29] Colon Rectal bleeding 32 M 2 Polypoid Monophasic t(X; 18) S 5
Schreiber-Fracklam et al., 2007 [30] Distal duodenum Abdominal pain 39 F 5 Polypoid Monophasic t(X; 18), SSX2 S+Chemo Recurrence 8 months after surgery
Makhlouf et al., 2008 [32] Stomach   67 F 0.8   Monophasic t(X; 18) S AWOD, 12
Makhlouf et al., 2008 [32] Stomach   49 M 2   Monophasic with a poorly differentiated component t(X; 18) S DOD, omental metastasis, 29
Makhlouf et al., 2008 [32] Stomach   68 F 2   Monophasic t(X; 18) S AWOD, 22
Makhlouf et al., 2008 [32] Stomach   29 M 2.8   Monophasic t(X; 18) S AWOD, 224
Makhlouf et al., 2008 [32] Stomach, gastrodudenal junction   54 F 3   Monophasic t(X; 18) S Recent case
Makhlouf et al., 2008 [32] Stomach   58 F 3   Monophasic t(X; 18) S AWOD, 21
Makhlouf et al., 2008 [32] Stomach   37 F 4   Monophasic t(X; 18) S Local recurrence, re-excised. DOC 48
Makhlouf et al., 2008 [32] Stomach   50 M 6   Monophasic t(X; 18) S+Chemo Alive with recurrence, 6
Makhlouf et al., 2008 [32] Stomach   42 M 8 Polypoid Biphasic t(X; 18) S+Chemo DOD, 25
Makhlouf et al., 2008 [32] Stomach   66 F 15 Polypoid Monophasic t(X; 18) S Lost to follow-up
Company et al., 2009 [31] Proximal duodenum Weight loss asthenia anorexia, nausea, epigastric pain 69 F 8 Spherical, intramural Monophasic t(X; 18) S Died due to complications, 1
Present case, 2010 Ileum Abdominal pain, distension and heaviness 39 F 8 Intramural Monophasic - S AWOD, 6
  1. The second case reported by Billings [25] could represent a metastatic focus of a primary neck tumor as it showed the same histopathological features.
  2. AWOD = alive without evidence of disease; AWD = alive with residual disease; Chemo = chemotherapy; DOC = died of other cause; DOD = died of disease; NR = not reported; Rad = radiotherapy; S = surgery; SSX = synovial sarcoma-associated fusion transc; PDSS = Poorly difrentiated synovial sarcoma