Table 1 Summary of reported cases of radiological occult cancer infiltration of the liver
Presenting symptoms | Age (years) | Prior history of cancer | Radiological test | Reported findings | Other lab test | Biopsy/Autopsy results | Reference number |
|---|---|---|---|---|---|---|---|
Nausea, vomiting, abdominal pain | 36 | Ductal carcinoma 9 months prior | CT | No abdominal lesions | Increased LFTs | Breast cancer | 3 |
Anorexia and general fatigue | 46 | Mycosis fungoides | CT and US | Normal liver | 20-fold increased LFTs | Mycosis fungoides | 13 |
Mild fever with elevated LFTs | 50 | None | CT | Hepatomegaly | Elevated LFTs, low plts and HCT | Peripheral T-cell lymphoma | 12 |
Abdominal pain, decreased appetite | 54 | None | CT and US | Hepatomegaly and ascites | Low HCT | Small-cell lung cancer | 10 |
Worsening ascites, jaundice, and hematochezia | 54 | Breast cancer 9 years prior | CT US | Probable benign cysts, ascites | Elevated LFTs | Poorly differentiated adenocarcinoma | 4 |
Altered liver test | 57 | None | CT and US | Heterogeneous liver parenchyma | Thrombocytopenia | Breast lobular carcinoma | 5 |
Clinical signs of hepatocellular injury | 59 | Renal cell carcinoma | Liver MRI | Hepatomegaly | None reported | Renal cell carcinoma | 14 |
Anorexia and abdominal distension | 62 | None | US and CT | Hepatomegaly and ascites | Elevated CA-125 | Melanoma | 15 |
Abnormal liver function | 62 | None | CT and MRI | Marked liver enlargement, no lesions | Increased LFT | Small-cell lung cancer | 9 |
Acute hepatic failure | 68 | None | CT scan | Negative | High LFTs | Metastatic prostatic carcinoma. | 16 |
Gastrointestinal hemorrhage | 69 | None | CT | No liver metastatic disease | LFT elevation | Urothelial carcinoma | 8 |
Acute severe hepatic failure | 77 | T-cell lymphoma | CT and US | Homogeneous enlarged liver, no ascites | Bili 9.1, increase LFTs | Small cell carcinoma | 11 |
Infants with hepatosplenomegaly | <1 | None | CT /MRI | Liver enlargement | No biogenic amines | Neuroblastoma | 6 |