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Table 2 Accordance of the presented patient with the Yamaguchi criteria for the diagnosis of adult-onset Still’s disease

From: Suppurative necrotizing granulomatous lymphadenitis in adult-onset Still’s disease: a case report

Yamaguchi criteria (require the presence of five features, with at least two being major diagnostic criteria): Patient’s characteristics
Major Yamaguchi criteria:  
 1. Fever of at least 39°C lasting at least one week. +
 2. Arthralgias or arthritis lasting two weeks or longer.
 3. Typical rash (maculopapular, nonpruritic) during febrile episodes. +
 4. Leukocytosis (10,000/μL or greater), with at least 80% granulocytes. +
Minor Yamaguchi criteria:  
 1. Sore throat
 2. Lymphadenopathy +
 3. Hepatomegaly or splenomegaly
 4. Abnormal liver function studies
 5. Negative antinuclear antibodies and rheumatoid factor. +
Exclusions  
 1. Infection, especially sepsis and infectious mononucleosis
 2. Malignancies, especially lymphomas
 3. Rheumatic diseases known to mimic adult Still’s disease