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Figure 1 | Journal of Medical Case Reports

Figure 1

From: Successful immune tolerance induction consisting of high-dose factor VIII rich in von Willebrand factor and pulsed intravenous immunoglobulin: a case report

Figure 1

The time changes in initial inhibitor titer (IT) and factor VIII (FVIII) recovery before and during immune tolerance induction (ITI). IT constantly decreased after the FVIII discontinuation; during ITI, after the initial increase (up to 72.0BU/mL) in the first month (anamnestic response), a constant decrease in IT was seen with a transient low increase (up to 12.0BU/mL) during severe infection (catheter-related sepsis) in the second month; FVIII recovery continuously improved from the fourth month of ITI. BU = Bethesda unit; FVIII = factor VIII; FVIII P = prophylaxis with factor VIII; IT = inhibitor titer; ITI = immune tolerance induction; IU = international unit; rFVIIa = recombinant activated factor VII.

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Journal of Medical Case Reports

ISSN: 1752-1947