Figure 5From: Osteomyelitis and pyoarthritis resulting from local paracoccidioidomycosis in an immunocompetent patient: a case report (A) Paracoccidioides brasiliensis with multiple peripheral buds in the typical ‘pilot wheel’ configuration (arrow) (periodic acid-Schiff stain, 400×); (B) Birefringent rings, some of which show lateral budding cells being phagocytosed by multinucleated foreign-body giant cells (open arrow) (hematoxylin and eosin stain, 400×); and (C) the chronic granulomatous inflammatory process characterized by epithelioid cells and multinucleated giant cells surrounding the fungi (hematoxylin and eosin stain, 100×). Back to article page