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Table 1 Case reports of secondary malignancy following stereotactic radiosurgery

From: Radiation-induced glioma following CyberKnife® treatment of metastatic renal cell carcinoma: a case report

Reference

Patienta

Indication for radiation

Location of primary lesion

Latency period

Secondary malignancy

Location of secondary lesion

Comey 1998 [14]

44M

VS

Cerebellopontine angle

5 years

Triton tumor

Cerebellopontine angle

Noren 1998 [15]

18Fb

VS

Cerebellopontine angle

6 years

Triton tumor

Cerebellopontine angle

Thomsen 2000 [16]

19Fb

VS

Cerebellopontine angle

6 years

Meningosarcoma

Cerebellopontine angle

Yu 2000 [17]

70F

Meningioma

Occipital region

7 years

GBM

Occipital lobe

Kaido 2001 [18]

20M

AVM

Right parietal lobe

6.5 years

GBM

Right parietal lobe

Shamisa 2001 [19]

57F

VS

Cerebellopontine angle

7.5 years

GBM

Inferior temporal lobe

Bari 2002 [20]

30Fb

VS

Cerebellopontine angle

3.5 years

Malignant nerve sheath tumor

Cerebellopontine angle

Salvati 2003 [11]

66F

Cavernoma

Right frontal region

13 years

GBM

Right frontal, corpus callosum

Shin 2002 [21]

26F

VS

Cerebellopontine angle

6 years

Malignant nerve sheath

Cerebellopontine angle

McIver 2004 [22]

43F

Metastatic melanoma

Left parietal parasagittal region

5.3 years

Anaplastic astrocytoma

Cerebellum

Sanno 2004 [23]

53F

Meningioma

Falx cerebri

5 years

Osteosarcoma

Right parietal lobe

Sheehan 2006 [1]

7M

AVM

Right basal ganglia

12 years

Assumed meningioma (?)

Right lateral middle cranial fossa

Sheehan 2006 [1]

16F

AVM

Right temporal

10 years

Assumed meningioma (?)

Right temporal lobe

Balasubramaniam 2007 [24]

64Fb

AVM

Cerebellopontine angle

5 years

GBM

Right temporal lobe

Berman 2007 [25]

34F

AVM

Pineal region

9 years

GBM

Corpus callosum and/or right parietal lobe

Carlson 2009 [26]

15Fb

AVM

Bilateral posterior fossae

10 years

Rhabdomyosarcoma

Inferior right medulla and cerebellomedullary cistern

  1. aage at time of radiation.
  2. bpatient with neurofibromatosis 2.
  3. Abbreviations: AVM arteriovenous malformation, F female, GBM glioblastoma multiforme, M male, VS vestibular schwannoma.