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Table 2 Literature review of cases with extremely high serum ferritin

From: Hepatic tuberculosis presenting with extreme hyperferritinemia masquerading as adult-onset Still’s disease: a case report

Ref.

Sex/Age

Clinical features

Labs

Ferritin

Diagnosis

    

(ng/ml)

 

[17]

M/23y

Fever

WBC 5800/ mm3

13,547

HIV with milliary TB

  

Asthenia

   
  

Malaise

   

[18]

F/40d

Fever

WBC 2400/ mm3

25,534

Hemophagocytic lymphohistiocytosis

  

Lymphadenopathy

   
  

Hepatosplenomegaly

   

[19]

M/77y

Cardiac arrest

ALT; 4410IU/L

10,740

Acute hepatic damage

[19]

M/75y

Fever, hypotension

ALT;2530 IU/L

46,500

Septicemia

   

Iron: 12umol/L Tr.: 40%

  

[19]

F/64y

Liver transplant

ALT;5790IU/L

42,510

Post-operative Hepatic ischemia

   

Iron: 49 umol/L Tr. : 79%

  

[19]

F /59y

Liver transplant

ALT;1790IU/L Iron 26 umol/L Tr.t: 45%

15,100

Post-operative hepatic ischemia

[19]

F/61y

Cardiac catheterization

ALT : 2510IU/L

23,200

Dissection of coronary arteries and hypotension

[20]

F/49y

PUO Hepatosplenomegaly Pleural effusion Rash;erythema-multiform

Leucocytosis DIC Hemophagositic-syndrome

240,000

Breast carcinoma Paraneoplastic syndrome

  1. ALT alanine aminotransferase, DIC disseminated intravascular coagulation; F female; M male, PUO pyrexia of unknown origin, Ref reference, Tr transferrin saturation, WBC total white blood cells.