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Table 1 Yamaguchi criteria

From: Hepatic tuberculosis presenting with extreme hyperferritinemia masquerading as adult-onset Still’s disease: a case report

Major criteria

 

·

Fever ≥39°C (one week or longer)

·

Arthralgia and/or arthritis (two weeks or longer)

·

Non-pruritic, pink, macular or maculopapular rash, usually during febrile episodes (evanescent, salmon-pink rash)

·

Leucocytosis (>10,000mmol/L, >80% neutrophils)

Minor criteria

 

·

Pharyngitis

·

Lymphadenopathy and/or splenomegaly

·

Liver involvement (raised serum transaminases and/or lactate dehydrogenase)

·

Negative rheumatoid factors and antinuclear antibodies

  1. Diagnosis of adult-onset Still's disease needs five or more of the diagnostic criteria listed above, of which two must be major criteria.