Figure 1
From: Smoldering myeloma presenting as progressive multifocal leukoencephalopathy: a case report
In the initial scan, T2-weighted (A) axial magnetic resonance imaging scan demonstrates small foci of disease bilaterally (arrows). The diffusion-weighted image (B) shows mild hyperintensity of the lesion on the right (arrow). The postgadolinium T1-weighted image (C) shows no significant enhancement. In the scan obtained three weeks later, the T2-weighted image (D) reveals a mild change in the lesion on the right (arrow). The diffusion-weighted image (E) reveals a marked higher signal intensity as in (B) (arrow) and shows new lesions left-sided subcortically (arrowheads). The postgadolinium T1-weighted image (F) now demonstrates marked progression of disease with patchy enhancement of lesions bilaterally (arrowheads).