Table 1 Summary of 17 reported cases of primary pineal melanoma
Author | Year | Sex | Age (years) | Time to diagnosis (weeks) | Symptoms | Imaging | Melanic pigment | Treatment | Survival (weeks) | |
|---|---|---|---|---|---|---|---|---|---|---|
CT | MRI | |||||||||
Ogle [4] | 1899 | F | 32 | 3 | Headache, paralysis, aphasia | - | - | NR | None | 13 |
Stoerk | 1904 | M | 31 | 8 | PS, headache, diplopia | - | - | NR | None | 12 |
Foot | 1931 | M | 49 | 2 | Headache | - | - | present | None | 4 |
Gibson | 1952 | F | 68 | 8 | Headache, vomiting, coma | - | - | present | None | 8 |
Enriquez | 1973 | M | 43 | 32 | Left-sided weakness, changes in character | - | - | present | None | 37 |
Arland | 1977 | M | 56 | 40 | PS, gait disturbance, memory impairment | - | - | present | Radiation | 56 |
Carlson | 1987 | F | 77 | 1 | Gait disturbance, poor memory | - | - | NR | VPS, craniotomy, biopsy | 5 |
Weindling | 1988 | M | 59 | 2 | Headache, vomiting, papilledema | + | + | present | Biopsy | NR |
Rubino | 1992 | M | 60 | 4 | Gait disturbance, lethargy, diplopia, retraction nystagmus | + | + | present | Radical resection | >52 |
Yamane | 1994 | F | 60 | 2 | Headache, PS | + | + | present | Resection, chemotherapy | >280 |
Mitchell [6] | 1998 | M | 49 | 12 | Vomiting, weight loss, drowsiness | + | + | present | Biopsy | NR |
Suzuki | 2001 | F | 50 | 16 | Poor memory | + | + | present | Partial resection, radiation | 88 |
Bookland | 2006 | F | 20 | 3 | Headache, cervical pain | + | + | present | Biopsy, VPS, radiation and chemotherapy | >37 |
Barron | 2007 | F | 73 | NR | Headache, gait unsteadiness, double vision, memory change | + | + | present | Radiation | 69 |
Arantes [3] | 2010 | F | 54 | 16 | Gait disturbance, memory changes, lethargy, sphincters incontinence | + | + | present | Biopsy, VPS, resection, radiation and chemotherapy | >80 |
Cedeño DÃaz [5] | 2011 | M | 70 | 24 | Headache, gait disturbance, lethargy, diplopia | + | + | present | Partial resection, radiation | 40 |
Present case | 2011 | F | 22 | 5 | Headache, gait disturbance | + | + | present | Biopsy , radical resection, external ventricular drain | 7 |